A scenario where the complete elimination of microbial growth needs to be monitored is in Agriculture, more precisely meat production.
The use of antibiotics has been used recently in the mass production of fowl, pork, and beef. The elimination of microbes with antimicrobials has impacted different ecosystems such as the creation of new resistant pathogens and the destruction of microbiota.
In Agriculture, the ease of use of antimicrobials increases the production and the overall quality of life for animals, while causing various problems to other ecosystems. A few of these problems include the creation of resistant pathogens for humans and livestock and the destruction of healthy microbiota within the digestive systems in humans. As a result, the elimination of most microbes in animals has manifested with severe unwanted problems.
The big problem of eliminating or destroying all microbial life, in general, will always face humanity with difficulties. In one extreme, with no microbial life, most life would end, and some would have to adapt. We all have to die at some point, and all living matter that fades would no longer decay and piling up. The atmosphere would also change, reducing the oxygen-rich air. Just a few examples.
Finally, alternatives to this antibiotic problem exist. Although some other options are carcinogenic to life, others are not. Many produce using new farming techniques that involve closed systems, while they do cause other harm such as pollution. Medications that don’t include antibiotics are available and address specific diseases for animals, reducing spreading illness by reduction.